6月20至21日，德国AB Enzymes公司的执行官Dr. Karl-Heinz Maurer博士、斯图加特大学Rolf Schmid教授和亚琛工业大学Ulrich Schwaneberg教授应邀来所进行学术交流，分别作了题为“New proteases from fungi: application and production aspects”、“ Sino-German interactions in biotec R&D – status and perspectives”和“Steering directed monooxygenase evolution: concepts, lessons and prospects after fifteen years of P450 BM3 evolution”的学术报告。天津工生所田朝光研究员和涂然副研究员主持报告会。天津工生所副所长朱敦明研究员到会参加。
在报告中， Maurer博士介绍了近年德国AB Enzymes公司在真菌中发掘蛋白酶和产业化应用的最新研究进展，并结合他近30年的生物制剂（酶）的研发经验，对蛋白酶的新酶发掘途径、表达系统开发和产业化研究方向等方面进行了阐述和展望。Schmid教授介绍了德国相关科研领域和产业应用情况、中德双边项目合作情况等，详细阐述了科研单位与产业公司联盟合作的中德CLIB2021（工业生物技术集群）机构，并就促进创新产研合作模式提出了新的思路。Schwaneberg教授在报告中，以重要工业用酶——P450 BM-3单加氧酶为例，介绍了P450单加氧酶的定向进化改造进展和存在的挑战，并对单加氧酶的研究方法、酶催化机理和改造方向等方面进行详细阐述，为其他工业酶类的工程改造提供了经验借鉴。
报告人简介：
Dr. Karl-Heinz Maurer, Business Development Director at AB Enzymes GmbH (Darmstadt).
Karl-Heinz Maurer studied Biochemistry at the University of Tübingen and obtained his Dr degree in 1984. From 1985 to 1986, he was Resarch Associate at the University of Wisconsin in Madison (WI, USA). Between 1986 and 2010, he worked at Henkel in Düsseldorf (including different affiliated companies like COGNIS and COGNIS Biotechnology), with a focus on corporate research such as a corporate director Biotechnology within the Global R&D of the business unit Laundry and Home Care. Since 2011 he was appointed as Business Development Director at AB Enzymes GmbH (Darmstadt) responsible for new business development and regulatory affairs.
Prof. Dr. Rolf Schmid, Founder and Director of Bio4Business, Coordinator of the Bilateral Cooperations of the State of Baden-Wurttemberg.
Rolf Schmid graduated in chemistry at the Universities of Munich and Freiburg and obtained his Dr degree in 1970. After Post-doctoral training in France and in the USA he moved to Henkel Dusseldorf. In 2007, he obtained MBA degree from the University of Reutlingen. Throughout his career, he was involved in activities and projects in Japan and more recently in China. He is Honorary Professor of Nanjing University of Technology. Since 2009, he is coordinator for the Bilateral Cooperations of the State of Baden-Wurttemberg in the Field of Biotechnology with the State's Asian partners in China and Japan.
Prof. Dr. Ulrich Schwaneberg, Director of the Institute of Biotechnology at RWTH Aachen University.
Ulrich Schwaneberg studied chemistry at the University of Stuttgart and received his Dr degree in 1999. Then, he moved as post-doctoral fellow to the lab of Prof. Frances H. Arnold at Caltech (USA) for two years. In January 2002, he was appointed as Assistant Professor at the Jacobs University Bremen and promoted in 2006 to the Associate Professor level and founded SeSaM-Biotech GmbH in 2008. In January 2009, he moved to the RWTH Aachen University as Head of the Institute of Biotechnology and was furthermore appointed in 2010 as Director within the DWI research center. Since 2010 he has been appointed as director in the Bioeconomy Science Center representing the RWTH Aachen University in a coordinative bioeconomy research initiative. He has a special interest in method development and tailoring of proteins for industrial biotechnology applications and interactive materials research.
Prof.Karl-Heinz Maurer
Prof.Rolf Schmid
Prof.Ulrich Schwaneberg
