[1] P. Zhang#, B. Yuan#, J. Li, C. Li, J. Guo, B. Zhang, G. Qu, H. Su, N. J. Turner, Z. Sun*, Biocatalytic Desymmetrization for the Atroposelective Synthesis of Axially Chiral Biaryls Using an Engineered Imine Reductase, Angew. Chem. Int. Ed, 2024, e202416569.
[2] J. Li#, B. Yuan#, C. Li, Z. Zhao, J. Guo, P. Zhang, G. Qu, Z. Sun*, Stereoselective Synthesis of Oxetanes Catalyzed by anEngineered Halohydrin Dehalogenase, Angew. Chem. Int. Ed, 2024, e202411326.
[3] P. Xie, J. Lan, J. Zhou, Z. Hu, J. Cui, G. Qu, B. Yuan*, Z. Sun*, Co-immobilization of amine dehydrogenase and glucose dehydrogenase for the biosynthesis of (S)-2-aminobutan-1-ol in continuous flow. Bioresour. Bioprocess, 2024, 11, 70.
[4] B. Yuan*, D. Yang, G. Qu, N. J. Turner* and Z. Sun*, Biocatalytic Reductive Aminations with NAD(P)H-Dependent Enzymes: Enzyme Discovery, Engineering and Synthetic Applications, Chem Soc Rev, 2024, 53, 227.
[5] M. Ye, C. Li, D. Xiao, G. Qu, B. Yuan* and Z. Sun*, Atroposelective Synthesis of Aldehydes via Alcohol Dehydrogenase-Catalyzed Stereodivergent Desymmetrization, JACS Au, 2024, 4, 411.
[6] X. Li, J. Wang, W. Su, C. Li, G. Qu, B. Yuan* and Z. Sun*, Characterization and Engineering of Cephalosporin C Acylases to Produce 7-Aminocephalosporanic Acid, Mol. Catal, 2023, 550, 113595.
[7] Y. Li, C. Bao, Z. Sun, W. Zhang* and B. Yuan*, Comparison Between Chemoenzymatic and Bienzymatic Cascades Leading to Morita–Baylis–Hillman Adducts, ChemCatChem, 2023, 15, e202201621.
[8] W. Huang, S. Huang, Z. Sun, W. Zhang, Z. Zeng* and B. Yuan*, Chemoenzymatic Synthesis of Sterically Hindered Biaryls by Suzuki Coupling and Vanadium Chloroperoxidase Catalyzed Halogenations, ChemBioChem, 2023, 24, e202200610.
[9] S. Song#, Y. Jiang#, R. Chen, W. Su, W. Liang, D. Yang, J. Li, W. Zhang, S. Gao, B. Yuan*, G. Qu*, Z. Sun*, Whole-Cell Biotransformation of Penicillin G by a Three-Enzyme Co-expression System with Engineered Deacetoxycephalosporin C Synthase. ChemBioChem, 2022, 23, e202200179.
[10] B. Yuan, D. Mahor, Q. Fei, R. Wever, M. Alcalde, W. Zhang*, F. Hollmann*, Water-Soluble Anthraquinone Photocatalysts Enable Methanol Driven Enzymatic Halogenation and Hydroxylation Reactions, ACS Catalysis, 2020, 10, 8277.
[11] B. Yuan, D. Debecker, X. Wu, J. Xiao, Q. Fei*, N. J. Turner*, One-pot Chemoenzymatic Deracemisation of Secondary Alcohols Employing Variants of Galactose Oxidase and Transfer Hydrogenation, Chemcatchem, 2020, 12, 6191.
[12] B. Yuan, A. Page, C. P. Worrall, F. Escalettes, S. C. Willies, J. J. W. McDouall, N. J. Turner* and J. Clayden*, Biocatalytic Desymmetrization of an Atropisomer with both an Enantioselective Oxidase and Ketoreductases, Angew. Chem. Int. Ed, 2010, 49, 7010.
[13] T. Cui#, B. Yuan#, H. Guo, H. Tian, W. Wang, Y. Ma, C. Li, Q. Fei*,Enhanced Lignin Biodegradation By Consortium Of White Rot Fungi: Microbial Synergistic Effects And Product Mapping, BIOTECHNOL BIOFUELS, 2021, 14, 162.
[14] B. Yuan, F. Escalettes, N. J. Turner*, Practical Methods for Biocat. and Biotrans. 2, Chapter 6.2 & Chapter 6.3, 2012, John Wiley & Sons, Ltd.
[15] Qin Z, Yuan B, Qu G*, Sun Z*. Rational enzyme design by reducing the number of hotspots and library size. Chem. Commun., 2024, 60, 10451-10463.
[16] H. Ming, B. Yuan, G. Qu*, Z. Sun*, Engineering the activity of Amine Dehydrogenase in the Asymmetric Reductive Amination of Hydroxyl Ketones, Catal. Sci. Technol, 2022, 12, 5952.
[17] Y. Li, B. Yuan, Z. Sun, W. Zhang* C-H Bond Functionalization Reactions Enabled by Photobiocatalytic Cascades, 2021, Green Synth. Catal., 2, 267.
[18] S. Staniland, B. Yuan, N. Gimenez-Agullo, T. Marcelli, S. C. Willies, D. M. Grainger, N. J. Turner*, and J. Clayden*, Enzymatic Desymmetrising Redox Reactions for the Asymmetric Synthesis of Biaryl Atropisomers, Chem. Eur. J., 2014, 20, 13084.
[19] Li Y, Yuan B, Sun Z, Zhang W. C–H bond functionalization reactions enabled by photobiocatalytic cascades. Green Synth. Catal., 2021, 2 (3), 267-274.
[20] Li X, Li C, Qu G, Yuan B, Sun Z*. Engineering of a Baeyer-Villiger monooxygenase to improve substrate scope, stereoselectivity and regioselectivity. ChemBioChem, 2024, e202400328.
[21] Wang Q, Li C, Yuan B, Yu A, Qu G*, Sun Z*. Engineering the activity of a newly identified arylalkylamine N-acetyltransferase in the acetylation of 5-hydroxytryptamine. ChemBioChem, 2024, e202400069.
[22] Ren Y, Qin Z, Li C, Yuan B, Yang Y, Qu G*, Sun Z*. Engineering the activity and thermostability of a carboxylic acid reductase in the conversion of vanillic acid to vanillin. J. Biotechnol., 2024, 386, 19-27.
[23] Paul C, Hanefeld U, Hollmann F*, Qu G, Yuan B, Sun Z. Enzyme engineering for biocatalysis. Mol. Catal., 2024, 555, 113874.
[24] Sang X, Tong F, Zeng Z, Wu M, Yuan B, Sun Z, Sheng X, Qu G, Alcalde M, Hollmann F, Zhang W. A Biocatalytic Platform for the Synthesis of Enantiopure Propargylic Alcohols and Amines. Org. Lett., 2022, 24(23), 4252-4257.
[25] 罗佳慧, 李聪聪, 叶梦静, 张鹏鹏, 曲戈, 蔡志强, 王车礼, 袁波*, 孙周通*. 含吡咯及吲哚基团的N-N轴手性化合物的酶催化合成[J]. 生物工程学报, 1-14. 10.13345/j.cjb.240512.
[26] 曲戈, 袁波, 孙周通. 工业蛋白质理性设计与应用[J]. 生物工程学报, 2022, 38(11): 4068-4080.
[27] 尚亚莉, 袁波, 费强. 生物催化轴手性化合物的不对称合成进展[J]. 高校化学工程学报, 2021, 35(5):14. 10.3969/j.issn.1003-9015.2021.05.003.
[28] 张武元, 袁波, 曲戈, 孙周通. 光促酶催化反应设计及生物合成应用[J]. 生物学杂志, 2021, 38(5): 1. 特约综述.
申请及授权发明专利
[1] 袁波, 孙周通, 张鹏鹏, 陈龙, 罗佳慧,一种沙库巴曲中间体的合成方法, 2023112695532, 2023.9.28;
[2] 袁波, 孙周通, 李湘莹, 苏文成,一种头孢菌素C酰化酶的人工合成及其突变体应用,202210655746.0, 2022.6.10;
[3] 袁波, 孙周通, 李湘莹, 苏文成,一种头孢菌素C酰化酶突变体及其应用, 202210655745.6, 2022.6.10;
[4] 袁波, 宋世怡, 李湘莹, 苏文成, 蒋迎迎, 曲戈, 孙周通, 张武元, 扩环酶及其突变体在生产G-7-ADCA中的应用, CN202110676893.1, 2021.6.18;
[5] 孙周通, 袁波, 苏文成, 李湘莹,一种头孢菌素C酰化酶催化的酰化反应及其应用,202210655575.1, 2022.6.10;
[6] 孙周通, 袁波, 苏文成, 李湘莹, 李金成,头孢菌素C酰化酶突变体及其在头孢菌素母核合成中的应用,202210655545.0,2022.6.10;
[7] 孙周通, 杨大猛, 李湘莹, 苏文成, 蒋迎迎, 曲戈, 张武元, 袁波,一种生产7-氨基去乙酰氧基头孢烷酸的方法,202111097082.2