郑平
1989.09-1993.07 山东大学微生物系,微生物工程专业,学士
1993.09-1996.07 山东大学微生物系,微生物学专业,硕士
1996.07-2000.09 齐鲁工业大学(原山东轻工业学院)食品工程系,助教/讲师
2001.10-2006.09 德国不伦瑞克工业大学/德国赫尔姆霍茨传染病研究中心(原德国国家生物工程中心GBF)生物工程/分子生物学专业,博士
2007.09-2008.06 德国赫尔姆霍茨传染病研究中心系统生物学研究组博士后
2008.07-2014.04 中国科学院天津工业生物技术研究所副研究员
2011.11-2013.07 中国科学院天津工业生物技术研究所技术支撑平台负责人
2014.05-至今 中国科学院天津工业生物技术研究所研究员2021年获天津市滨海新区第二批杰出科技人才
2020年获天津市最美科技巾帼
2019年获中国轻工业联合会科学技术进步奖
2019年获中国科学院科技促进发展奖
2017年获天津市三八红旗手
2016年获天津市滨海新区人大代表
2014年获中国产学研合作创新成果奖
1.Wang Y*, Cheng H, Liu Y, Liu Y, Wen Y, Zhang K, Ni X, Gao N, Fan L, Zhang Z, Liu J, Chen J, Wang L, Guo Y, Zheng P*, Wang M*, Sun J and Ma Y. In-situ generation of large numbers of genetic combinations for metabolic reprogramming via CRISPR-guided base editing. Nat Commun. 2021, 12:678. https://doi.org/10.1038/s41467-021-21003-y
2.Sun X#, Li Q#, Wang Y#, Zhou W, Guo Y, Chen J, Zheng P*, Sun J*, Ma Y. Isoleucyl-tRNA synthetase mutant based whole-cell biosensor for high-throughput selection of isoleucine overproducers.Biosens Bioelectron. 2021,172.
3.Fan L, Wang Y*, Qian J, Gao N, Zhang Z, Ni X, Sun L, Yuan Q, Zheng P* and Sun J.Transcriptome analysis reveals the roles of nitrogen metabolism and sedoheptulose bisphosphatase pathway in methanol-dependent growth of Corynebacterium glutamicum.Microb Biotechnol. 2021.
4.Wang Y*, Liu Y, Zheng P, Sun J and Wang M*. Microbial Base Editing: A Powerful Emerging Technology for Microbial Genome Engineering. Trends Biotechnol. 2020.
5.Wang Y, Fan L, Tuyishime P, Zheng P*, Sun J*. Synthetic Methylotrophy: A Practical Solution for Methanol-Based Biomanufacturing. Trends Biotechnol. 2020.
6.Zhang Z, Wang Y *, Zheng P* and Sun J.Promoting Lignin Valorization by Coping with Toxic C1 Byproducts. Trends Biotechnol. 2020.
7.Chen J #, Wang Y # , Guo X, Rao D, Zhou W, Zheng P*, Sun J * and Ma Y.Efficient bioproduction of 5?aminolevulinic acid, a promising biostimulant and nutrient, from renewable bioresources by engineered Corynebacterium glutamicum. Biotechnol Biofuels. 2020, 13(1)
8.Li M #, Chen J #, Wang Y, Liu J, Huang J, Chen N, Zheng P* and Sun J *. Efficient Multiplex Gene Repression by CRISPR-dCpf1 in Corynebacterium glutamicum. Front Bioeng Biotechnol. 2020, 8:357.
9.Zhang L #, Zheng X #, Cairns TC, Zhang Z, Wang D*, Zheng P* and Sun J. Disruption or reduced expression of the orotidine?5,?decarboxylase gene pyrG increases citric acid production: a new discovery during recyclable genome editing in Aspergillus niger. Microb Cell Fact. 2020, 19(1):1-12.
10.Dele-Osibanjo T#, Li Q #, Zhang X #, Guo X, Feng J, Liu J, Sun X, Wang X, Zhou W, Zheng P*, Sun J*, Ma Y. Growth-coupled evolution of phosphoketolase to improve l-glutamate production by Corynebacterium glutamicum. Appl Microb Biotech. 2019
11.Wang W#, Li Q#, Sun C, Cai Z, Zheng X, Guo X, Ni X, Zhou W, Guo Y, Zheng P*, Chen C, Sun J*, Li Y, Ma Y. GREACE-assisted adaptive laboratory evolution in endpoint fermentation broth enhances lysine production by Escherichia coli. Microb Cell Fact. 2019
12.Wang Y#, Liu Y#, Li J, Yang Y, Ni X, Cheng H, Huang H, Guo Y, Ma H, Zheng P*, Wang M*, Sun J, Ma Y. Expanding targeting scope, editing window, and base transition capability of base editing in Corynebacterium glutamicum. Biotech Bioeng. 2019
13.Zhu C#, Chen J#, Wang Y, Wang L, Guo X, Chen N, Zheng P*, Sun J*, Ma Y. Enhancing 5‐aminolevulinic acid tolerance and production by engineering the antioxidant defense system of Escherichia coli. Biotechnol Bioeng. 2019
14.Sun D#, Chen J#, Wang Y, Li M, Rao D, Guo Y, Chen N, Zheng P*, Sun J*, Ma Y. Metabolic Engineering of Corynebacterium glutamicum by Synthetic Small Regulatory RNAs. J Industr Microb & Biotech, 2019, 46 (2): 203–208.
15.Tuyishime P#, Wang Y#, Fan L, Zhang Q, Li Q, Zheng P*, Sun J*, Ma Y. Engineering Corynebacterium glutamicum for methanol-dependent growth and glutamate production. Metab Eng, 2018, 49:20-231.
16.Wang Y#, Liu Y #, Liu J, Guo Y, Fan L, Ni X, Zheng X, Wang M*, Zheng P*, Sun J*, Ma Y. MACBETH: Multiplex automated Corynebacterium glutamicum base editing method. Metab Eng, 2018, 47: 200-210.
17.Zheng X, Zheng P, Zhang K, Cairns TC, Meyer V, Sun J*, Ma Y. 5S rRNA Promoter for Guide RNA Expression Enabled Highly Efficient CRISPR/Cas9 Genome Editing in Aspergillus niger. ACS Synth Biol., 2018, e7b00456.
18.Zhang Q#, Zheng X#, Wang Y, Yu J, Zhang Z, Dele-Osibanjo T, Zheng P*, Sun J*, Jia S, Ma Y. Comprehensive Optimization of the Metabolomics Methodology for Metabolite Profiling of Corynebacterium glutamicum. Appl Microb Biotech, 2018, 102 (16): 7113-7121.
19.Wang Y, Cao G, Xu D, Fan L, Wu X, Ni X, Zhao S, Zheng P*, Sun J*, Ma Y. A Novel L-Glutamate Exporter of Corynebacterium glutamicum. Appl Enviro Microb, 2018, 84(6): e02691-17
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