2010.9-2014.7，北京化工大学 生物工程 学士

2014.9-2017.6，北京化工大学 化学工程与技术 硕士

2017.9-2021.6，北京化工大学 化学工程与技术 博士

2019.12-2020.12，德国 马克斯普朗克煤炭研究所 访问学生

2022.1-2025.1，西湖大学工学院 助理研究员

2025.5-2025.6，西湖大学工学院 访问学者

2025.9-今，中国科学院天津工业生物技术研究所 副研究员

计算生物学；低碳合成生物学；人工智能辅助蛋白质工程

1. Liu,J.^#,Zhang,H.^#,Xu,Y.,Meng,H.,& Zeng,A. P*. (2023). Turn air-captured CO2 with methanol into amino acid and pyruvate in an ATP/NAD (P) H-free chemoenzymatic system. Nature Communications,2023,14(1),2772.

2. H Zhang,Y Li,J Nie,J Ren*,AP Zeng*. Structure-based dynamic analysis of the glycine cleavage system suggests key residues for control of a key reaction step[J]. Communications Biology,2020,3(1):1-12.

3. Zheng,J.,H Zhang.,Xu,Q.,Zeng,A.,& Li,S.Z. MetaEnzyme: Meta Pan-Enzyme Learning for Task-Adaptive Redesign. 2024(1721–1730).Melbourne VIC,Australia.

4. L Cheng^#,H Zhang^#,Cui H,Cheng J,WY Wang;Wei B,Liu F,Liang H,XL Shen*,QP Yuan*. A novel α-L-rhamnosidase renders efficient and clean production of icaritin. Journal of Cleaner Production,2022,341,130903.

5. L Cheng^#,H Zhang^#,H Cui,Mehdi D. Davari,WY Wang*,QP Yuan*. Efficient enzyme-catalyzed production of diosgenin: inspired by the biotransformation mechanisms of steroid saponins in Talaromyces stollii CLY-6[J]. Green Chemistry,2021,23,5896-5910.

6. L Cheng,H Zhang,H Cui,WY Wang*,QP Yuan*. Efficient production of the anti-aging drug Cycloastragenol: insight from two Glycosidases by enzyme mining[J]. Applied Microbiology and Biotechnology,2020,104(23):9991-10004.

7. L Cheng, H Zhang,H Liang,X Sun,X Shen,J Wang,WY Wang*,QP Yuan*. Enzymatic Bioconversion of Cycloastragenol-6-O-β-D-glucoside into Cycloastragenol by a Novel Recombinant β-Glucosidase from Phycicoccus sp. Soil748 [J]. Process Biochemistry,2020,90: 81-88.